Chronic Intestinal Pseudo-Obstruction (CIPO) and related gastrointestinal motility disorders constitute a group of rare but debilitating conditions that mimic mechanical obstruction despite the ... This topic review will discuss the etiology, clinical manifestations, diagnosis, and treatment of chronic intestinal pseudo-obstruction (CIPO). The management of CIPO, acute colonic pseudo-obstruction, and slow transit constipation are discussed separately.

Understanding the Context

Chronic intestinal pseudo-obstruction (CIP) is defined by either continuous or intermittent symptoms of bowel obstruction in the absence of fixed lumen excluding lesion. Chronic intestinal pseudo-obstruction (CIPO) is a very rare syndrome with chronic and recurrent symptoms that suggest intestinal obstruction in the absence of any mechanical blockage of the lumen. [3] . The most common symptoms of CIPO include abdominal pain, constipation, nausea, vomiting, dysphagia, and abdominal distention.

Key Insights

In intestinal pseudo-obstruction, the intestine does not contract and push food, stool, and air through the digestive tract. The chronic disorder most often affects the small intestine, but can also occur in the large intestine (colon). The acute disorder usually affects the large intestine. Abstract Chronic intestinal pseudo-obstruction (CIPO) is a rare and life-threatening digestive disorder characterized by significantly reduced intestinal peristalsis, leading to the pathological intestinal dilatation and persistent obstructive symptoms without any mechanical cause. Etiologically, CIPO is classified into idiopathic and secondary.

Final Thoughts

Chronic intestinal pseudo-obstruction (CIPO) is a rare, severe and disabling gastrointestinal motility disorder. CIPO may involve multiple areas of the gastrointestinal tract, including the esophagus, stomach, small intestine, large intestine and rectum. This topic review will discuss the management of chronic intestinal pseudo-obstruction (CIPO). The etiology, clinical manifestations, and diagnosis of CIPO, acute colonic pseudo-obstruction (Ogilvie syndrome), chronic intestinal dysmotility, and slow transit constipation/colon inertia are discussed separately. What is Intestinal Pseudo-Obstruction? Intestinal pseudo-obstruction is a rare and chronic disorder characterized by impaired movement of the intestines, which resembles a blockage but lacks any physical impediment.

The condition can affect any part of the gastrointestinal tract but most commonly impacts the small and large intestines. The impaired motility can lead to symptoms similar to ... Chronic intestinal pseudo-obstruction (CIP) is a rare, potentially disabling gastrointestinal disorder characterized by abnormalities affecting the involuntary, coordinated muscular contractions (a process called peristalsis) of the gastrointestinal (GI) tract. Chronic intestinal pseudo-obstruction (CIPO) is a rare disease characterized by repetitive episodes or continuous symptoms of bowel obstruction when no blockage exists.