DEAR DR. ROACH: I am 71 years old and was diagnosed with pernicious anemia in October 2024. My B12 and folate levels were low.

Understanding the Context

My antiparietal antibodies were abnormal, but the intrinsic factor ... Intrinsic Factor: The main issue with intrinsic factor is that it helps with absorption of B12 (a vitamin) and a low B12 level will eventually effect your red blood cells. The optimal way to prevent this in those with intrinsic factor depletion is to supplement their B12 intake with injections that bypass the GI tract. Depends on the test: The test for intrinsic factor is usually antibody to intrinsic factor and that would not be affected.

Key Insights

If the B12 test is measuring the blood level of the vitamin, then that would be affected and yield a higher reading than the baseline, without the B 12 supplement. Does taking b12 a week before an intrinsic factor blood ... - HealthTap No: Vitamin B12 is absorbed through the stomach, and needs a particular hormone secreted by the stomach (intrinsic factor). Gastric bypass can cause B12 deficiency, or low dietary intake. The gall bladder just stores bile which is necessary for metabolizing fats, and isn't related to B12 absorption.

Final Thoughts

Intrinsic factor: Not available so you have to get shots of B-12. You can take B-12 orally. IF is used by the body to reabsorb it after it is secreted. On the first pass you should absorb more than enough. I got my intrinsic factor antibody test back as equivocal. how long should i wait before retesting to see if its positive or negative?

i will ask my gi but am looking for other opinions please. thank you? I got my intrinsic factor antibody test back as equivocal. how long ...