A genetic evaluation demonstrated Klinefelter syndrome 47, XXY karyotype with concurrent duplication of 3p21.31 by microarray analysis. We report on a boy who met DSM-IV criteria for autistic disorder in whom genetic studies revealed classic Klinefelter syndrome (KS) 47, XXY karyotype, while comparative genomic hybridization (CGH ... Medscape: Autism Spectrum Disorder, Klinefelter Syndrome, and Chromosome 3p21.31 Duplication: A Case Report Autism Spectrum Disorder, Klinefelter Syndrome, and Chromosome 3p21.31 Duplication: A Case Report Klinefelter syndrome is a genetic condition that affects only males.

Understanding the Context

Here's what you should know about the causes, symptoms, and treatment options for the condition. Klinefelter syndrome is a genetic ... People often feel confused or concerned when they first hear about Klinefelter syndrome and gynecomastia. The post Klinefelter Syndrome and Gynecomastia: Causes, Symptoms, Treatment appeared first on ...

Key Insights

Dermatologically, patients with Klinefelter's syndrome can show a higher percent of systemic lupus erythematosus and other skin-related autoimmune diseases than the normal population. A new study found that children with Klinefelter syndrome had significantly higher rates of sleep disorders than control individuals, highlighting the need for early screening. Patients with Klinefelter and triple X syndromes show an increased prevalence of SLE and Sjögren disease, likely due to the synergistic interaction of the extra X chromosomes.